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10月16日周五
  1. Mira Murati22

    今年最棒的部分之一,无论是在 Thinky 内部还是外部,就是看着人们追随自己的想法,一路走到他们自己拥有的权重之中。

    引用Thinking Machines@thinkymachines

    Tinker lets customers turn their expertise into cutting-edge models that they own. One year after launch, we look back at what we’ve shipped and what our users are building. https://thinkingmachines.ai/news/one-year-of-tinker/

10月15日周四
  1. OpenAI40

    OpenAI 向 Simons Foundation 新计划出资 500 万美元,用于帮助数学家检验、理解并在此基础上推进 AI 产出的结果,包括 OpenAI 近期发布的研究成果。

    引用Simons Foundation@SimonsFdn

    How can the math community forge the best path forward in the AI age? We're committing $15M to workshops and initiatives — plus free AI computing resources for foundation-supported researchers — through new partnerships with @AnthropicAI and @OpenAI: https://bit.ly/4zpfIbW #math #science #AI

  2. Latent Space58

    Leash Bio 的 Ian Quigley 谈 DEL 数据、Hermes 模型与智能体科学推理沙盒

    Latent Space 播客访谈 Leash Bio 的 Ian Quigley,讨论该公司如何用 DNA 编码库(DEL)获取高通量蛋白与小分子结合数据,并训练出在公开基准上跟上 Boltz 的 Hermes 模型。访谈还提到他们用多年积累的数据搭建智能体科学推理沙盒,让 LLM 在 6.5M 分子、100 次预算内寻找最佳结合物,相关预印本、博客和开放数据集即将发布。

10月13日周二
  1. Microsoft Research58

    微软研究院提出 StudentSim:用学生模拟器为 AI 辅导系统提供反馈

    微软研究院发布研究系统 StudentSim,用公开的去标识化学习记录训练个性化 AI 学生模拟器,在真实学习者测试之前评估和改进 AI 辅导系统。该系统采用两阶段训练,先在同学科多学生记录上学习共性,再针对单个学生适配,并配套提出覆盖国际象棋、第二语言英语写作和数学的评测协议 StudentSimEval。

10月12日周一
10月10日周六
10月9日周五
10月7日周三
10月6日周二
10月3日周六
10月2日周五
10月1日周四
9月30日周三
  1. Google DeepMind66

    Google DeepMind 推出 SynthID Bio,为 AI 生成的蛋白质加可验证水印

    Google DeepMind 发布 SynthID Bio,把水印技术引入合成生物学,将不可感知的签名嵌入生物代码,在实验室测试中保持蛋白质生物功能不变。该方法针对序列微调氨基酸选择、针对 3D 结构调整原子坐标,并在 AlphaFold 3 扩散网络中微调部分权重,使预测坐标自带可检测签名。

    推荐理由:Google DeepMind 把 SynthID 水印扩展到合成生物学,读者可了解其在蛋白质设计与结构预测中的嵌入方式及生物安全用途。

9月29日周二
  1. Microsoft Research62

    微软研究院推出面向生物学复杂性的 AI 研究系统 Quine

    微软研究院推出 Quine,一个由跨模态生物学世界模型和连接模型、科学工具、文献与研究者的交互框架组成的 AI 研究系统。该系统与 Broad Institute 合作用于胰腺导管腺癌研究,从数千个化合物中筛选并优先排序候选分子,湿实验显示排名最高的化合物产生了最大的经典态到基底态细胞状态转变,整个筛选到候选验证过程仅用一个周末。

    推荐理由:微软研究院公开 Quine 的生物学世界模型与实验编排框架,并给出胰腺癌化合物筛选的湿实验验证结果。

  2. Microsoft Research22

    Microsoft Research Asia 新加坡实验室成立一周年:推进前沿 AI 研究与产学研合作

    Microsoft Research Asia 新加坡实验室迎来成立一周年,这是微软在东南亚的首个研究实验室。该实验室围绕下一代 AI 模型与智能体系统、领域专用 AI、AI 原生研究实践、生态与人才培养四大方向展开工作,并在医疗健康领域与新加坡本地伙伴合作推进多模态医疗 AI 与自进化诊断智能体的落地。

9月24日周四
9月11日周五
9月10日周四
9月9日周三
9月8日周二
9月6日周日
9月3日周四
7月26日周日
7月11日周六
  1. Mira Murati58

    Mira Murati 回顾 Thinking Machines Lab 成立一年来的方向,聚焦多模态 AI、定制模型与开放科学。她提到团队已预览可像人一样协作的交互模型,Tinker 让任何人都能训练自己的开放权重模型,并发布了关于 Connectionism 的研究。她表示未来几个月将分享首款产品,其中包含重要的开源组件,面向研究者和开发定制模型的初创公司。

    引用Mira Murati@miramurati

    Thinking Machines Lab exists to empower humanity through advancing collaborative general intelligence. We're building multimodal AI that works with how you naturally interact with the world - through conversation, through sight, through the messy way we collaborate. We're excited that in the next couple months we’ll be able to share our first product, which will include a significant open source component and be useful for researchers and startups developing custom models. Soon, we’ll also share our best science to help the research community better understand frontier AI systems. To accelerate our progress, we’re happy to confirm that we’ve raised $2B led by a16z with participation from NVIDIA, Accel, ServiceNow, CISCO, AMD, Jane Street and more who share our mission. We’re always looking for extraordinary talent that learns by doing, turning research into useful things. We believe AI should serve as an extension of individual agency and, in the spirit of freedom, be distributed as widely and equitably as possible.  We hope this vision resonates with those who share our commitment to advancing the field. If so, join us. https://thinkingmachines.paperform.co/

7月7日周二
  1. Berkeley AI Research42

    智能免费之后怎么办?面向智能体、由智能体构建的数据系统

    UC Berkeley 团队提出,推理成本已从 GPT-4 级约 $30/百万 token 降至不足 $1,部分厂商低于 $0.10,基准测试中推理价格每年下降 9x 至 900x、中位数约 50x。作者据此提出三类数据系统挑战:为智能体设计的数据系统、支撑智能体群体运行的数据系统、以及由智能体合成的数据系统。

7月1日周三
5月20日周三
5月8日周五
  1. Berkeley AI Research36

    自适应并行推理:高效推理扩展的下一个范式

    伯克利 AI 研究团队综述并行推理进展,重点分析自适应并行推理——让模型自行决定何时分解并并行化子任务、开多少并发线程以及如何协调。现有方法如 self-consistency、Best-of-N、Tree of Thoughts、MCTS、ParaThinker、GroupThink 和 Hogwild! Inference 的并行结构多由外部设定,而非模型自主选择。

4月20日周一
  1. Berkeley AI Research38

    Berkeley AI Research 提出 GRASP:面向世界模型长时程规划的梯度规划器

    Berkeley AI Research 提出 GRASP,一种面向学习型世界模型的梯度规划器,通过将轨迹提升到虚拟状态实现跨时间并行优化、在状态迭代上直接注入随机性以促进探索,并重塑梯度让动作获得清晰信号。该方法针对长时程规划中梯度爆炸/消失、非贪心结构导致局部极小值以及高维视觉模型状态-输入梯度脆弱等问题,使基于梯度的长时程规划更稳健。

4月5日周日
  1. Andrej Karpathy60

    Karpathy 转发并点评 Farza 用 LLM 把 2,500 条日记、Apple Notes 和 iMessage 记录整理成含 400 篇文章的个人 Wiki(Farzapedia),认为这是个人化 AI 的好范例。

    引用Farza 🇵🇰🇺🇸@FarzaTV

    This is Farzapedia. I had an LLM take 2,500 entries from my diary, Apple Notes, and some iMessage convos to create a personal Wikipedia for me. It made 400 detailed articles for my friends, my startups, research areas, and even my favorite animes and their impact on me complete with backlinks. But, this Wiki was not built for me! I built it for my agent! The structure of the wiki files and how it's all backlinked is very easily crawlable by any agent + makes it a truly useful knowledge base. I can spin up Claude Code on the wiki and starting at index.md (a catalog of all my articles) the agent does a really good job at drilling into the specific pages on my wiki it needs context on when I have a query. For example, when trying to cook up a new landing page I may ask: "I'm trying to design this landing page for a new idea I have. Please look into the images and films that inspired me recently and give me ideas for new copy and aesthetics". In my diary I kept track of everything from: learnings, people, inspo, interesting links, images. So the agent reads my wiki and pulls up my "Philosophy" articles from notes on a Studio Ghibli documentary, "Competitor" articles with YC companies whose landing pages I screenshotted, and pics of 1970s Beatles merch I saved years ago. And it delivers a great answer. I built a similar system to this a year ago with RAG but it was ass. A knowledge base that lets an agent find what it needs via a file system it actually understands just works better. The most magical thing now is as I add new things to my wiki (articles, images of inspo, meeting notes) the system will likely update 2-3 different articles where it feels that context belongs, or, just creates a new article. It's like this super genius librarian for your brain that's always filing stuff for your perfectly and also let's you easily query the knowledge for tasks useful to you (ex. design, product, writing, etc) and it never gets tired. I might spend next week productizing this, if that's of interest to you DM me + tell me your usecase!

  2. Andrej Karpathy62

    Andrej Karpathy 在推文走红后,把用 LLM 构建个人知识库的方法整理成一份 gist 格式的 idea file,可直接交给智能体按需搭建。该流程把文章、论文、仓库等原始资料索引到 raw/ 目录,由 LLM 增量编译成 .md 维基,包含摘要、反向链接和概念文章,并在 Obsidian 中查看与提问。

    引用Andrej Karpathy@karpathy

    LLM Knowledge Bases Something I'm finding very useful recently: using LLMs to build personal knowledge bases for various topics of research interest. In this way, a large fraction of my recent token throughput is going less into manipulating code, and more into manipulating knowledge (stored as markdown and images). The latest LLMs are quite good at it. So: Data ingest: I index source documents (articles, papers, repos, datasets, images, etc.) into a raw/ directory, then I use an LLM to incrementally "compile" a wiki, which is just a collection of .md files in a directory structure. The wiki includes summaries of all the data in raw/, backlinks, and then it categorizes data into concepts, writes articles for them, and links them all. To convert web articles into .md files I like to use the Obsidian Web Clipper extension, and then I also use a hotkey to download all the related images to local so that my LLM can easily reference them. IDE: I use Obsidian as the IDE "frontend" where I can view the raw data, the the compiled wiki, and the derived visualizations. Important to note that the LLM writes and maintains all of the data of the wiki, I rarely touch it directly. I've played with a few Obsidian plugins to render and view data in other ways (e.g. Marp for slides). Q&A: Where things get interesting is that once your wiki is big enough (e.g. mine on some recent research is ~100 articles and ~400K words), you can ask your LLM agent all kinds of complex questions against the wiki, and it will go off, research the answers, etc. I thought I had to reach for fancy RAG, but the LLM has been pretty good about auto-maintaining index files and brief summaries of all the documents and it reads all the important related data fairly easily at this ~small scale. Output: Instead of getting answers in text/terminal, I like to have it render markdown files for me, or slide shows (Marp format), or matplotlib images, all of which I then view again in Obsidian. You can imagine many other visual output formats depending on the query. Often, I end up "filing" the outputs back into the wiki to enhance it for further queries. So my own explorations and queries always "add up" in the knowledge base. Linting: I've run some LLM "health checks" over the wiki to e.g. find inconsistent data, impute missing data (with web searchers), find interesting connections for new article candidates, etc., to incrementally clean up the wiki and enhance its overall data integrity. The LLMs are quite good at suggesting further questions to ask and look into. Extra tools: I find myself developing additional tools to process the data, e.g. I vibe coded a small and naive search engine over the wiki, which I both use directly (in a web ui), but more often I want to hand it off to an LLM via CLI as a tool for larger queries. Further explorations: As the repo grows, the natural desire is to also think about synthetic data generation + finetuning to have your LLM "know" the data in its weights instead of just context windows. TLDR: raw data from a given number of sources is collected, then compiled by an LLM into a .md wiki, then operated on by various CLIs by the LLM to do Q&A and to incrementally enhance the wiki, and all of it viewable in Obsidian. You rarely ever write or edit the wiki manually, it's the domain of the LLM. I think there is room here for an incredible new product instead of a hacky collection of scripts.

4月3日周五