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今天10月22日周四1 条
  1. elvis42

    告别上下文工程,迎来缓存工程。 玩笑归玩笑,这篇论文对这个问题采取了一种有趣的思路。

    引用DAIR.AI@dair_ai

    We love papers that go deeper down the stack. This is a good example that shifts from agentic context engineering to agentic cache engineering. They also apply recursive self-improvement to cache policies to further reduce cost by 7.1% over expert design. Specifically, this work focuses on KV cache management in long-running agents. When an agent summarizes or trims its history, the prefix change invalidates the cache after it, and the retained context must be prefilled again. Cache engineering gives the agent two operations on its own KV cache. One removes entries from future attention, and the other shifts the positions of the keys that remain. The trajectory text stays unchanged. This essentially provides a programmable interface for agents to define and refine their own cache engineering strategies. A rolling drop of old tool responses scores 1.7 points higher and costs 27.7% less than threshold-triggered summarization. Their AKV serving engine adds up to 1.2x throughput and 1.5x faster P95 latency. https://arxiv.org/abs/2610.28577 Chat with Paper: https://academy.dair.ai/papers/cache-engineering-for-agents-2610.28577

10月21日周三
  1. Rohan Paul78

    OpenAI 与 PerturbAI、Scripps Research 用 1946 个 GPT-Rosalind-5.5 智能体并行解析小鼠全脑 CRISPR 图谱,32 分钟完成其估计人类需数月的工作,产出脑疾病研究线索排序。

    引用OpenAI@OpenAI

    GPT-Rosalind surfaced a new lead for drug discovery: could restoring cholesterol transport protect neurons from degeneration? DCTN1 is a gene linked to Perry syndrome, a rare neurodegenerative disorder. In mouse-brain data, disrupting it increased expression of genes involved in making cholesterol. GPT-Rosalind suggested a possible explanation: cholesterol may not be reaching where neurons need it. That gives scientists a specific mechanism to test and, if confirmed, a direction for developing new treatments for neurodegenerative disorders. With @perturbai_tx and @scrippsresearch, a team of thousands of GPT-Rosalind agents worked in parallel, connecting gene-expression results from millions of mouse brain cells with scientific literature in just 32 minutes. We’re now expanding this collaboration to identify new drug targets. https://openai.com/index/scaling-ai-research-for-complex-biological-data/

    推荐理由:原文给出了智能体拆分大规模实验的具体做法与盲评对比数据,读者可据此判断并行智能体在科研分析中的分工方式。

  2. Rohan Paul75

    Anthropic 科学博客介绍,Claude 在其 Claude Science 环境中以智能体方式自主完成整套蛋白质设计流程,针对蝎毒神经毒素设计结合蛋白。

    引用Anthropic@AnthropicAI

    New on our Science Blog: designing protein binders against scorpion neurotoxins. Scorpions sting about 1.2m people every year, and antivenoms are often costly or in short supply. Claude has made an early step toward finding new treatments. https://www.anthropic.com/research/claude-scorpion-toxin-binder-design

    推荐理由:Anthropic 科学博客披露 Claude 作为智能体自主完成蛋白质设计流程,并给出两处实验室验证的分子数量。

10月20日周二
10月19日周一
10月17日周六
  1. Google DeepMind78

    Google DeepMind 转发介绍,四个 Gemini 4 Argon 智能体在同一个 Minecraft 世界中从零开始,用 27 小时击败末影龙。它们只在沙盒中用代码和文本操作,共编写 2,783 个程序,通过聊天分配任务、共享笔记并互相调试错误,全程没有人类帮助。

    引用Maxence Faldor@maxencefaldor

    Four Gemini 4 Argon agents, one shared Minecraft world, one goal: defeat the Ender Dragon. 27 hours and 2,783 self-written programs later, the dragon fell. https://x.com/i/article/2111007444981645312

    推荐理由:四个 Gemini 4 Argon 智能体在共享沙盒中自行分工、写码与调试,展示了多智能体协作完成长程任务的一种路径。

10月16日周五
10月15日周四
  1. Latent Space58

    Leash Bio 的 Ian Quigley 谈 DEL 数据、Hermes 模型与智能体科学推理沙盒

    Latent Space 播客访谈 Leash Bio 的 Ian Quigley,讨论该公司如何用 DNA 编码库(DEL)获取高通量蛋白与小分子结合数据,并训练出在公开基准上跟上 Boltz 的 Hermes 模型。访谈还提到他们用多年积累的数据搭建智能体科学推理沙盒,让 LLM 在 6.5M 分子、100 次预算内寻找最佳结合物,相关预印本、博客和开放数据集即将发布。

10月14日周三
10月13日周二
  1. Microsoft Research58

    微软研究院提出 StudentSim:用学生模拟器为 AI 辅导系统提供反馈

    微软研究院发布研究系统 StudentSim,用公开的去标识化学习记录训练个性化 AI 学生模拟器,在真实学习者测试之前评估和改进 AI 辅导系统。该系统采用两阶段训练,先在同学科多学生记录上学习共性,再针对单个学生适配,并配套提出覆盖国际象棋、第二语言英语写作和数学的评测协议 StudentSimEval。

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